These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Primary pulmonary malignant fibrous histiocytoma: case report and literature review.
    Author: Li X, Liu R, Shi T, Dong S, Ren F, Yang F, Ren D, Fan H, Wei S, Chen G, Chen J, Xu S.
    Journal: J Thorac Dis; 2017 Aug; 9(8):E702-E708. PubMed ID: 28932590.
    Abstract:
    Malignant fibrous histiocytoma (MFH) is an aggressive soft tissue sarcoma known to occur in various organs. Primary MFH arising in the lung is quite rare. Herein we report a case of a 61-year-old male with primary pulmonary MFH and explore the underlying molecular mechanisms by next-generation sequencing (NGS). Five gene mutations in TSC2, ARID1B, CDK8, KDM5C and CASP8 were detected, and the mTOR inhibitor might be an effective treatment for this patient. In addition, we reviewed the scientific literature of approximately 23 primary pulmonary MFH case reports since 1990 and summarized the clinical features and prognosis of this rare pulmonary malignant tumor.
    [Abstract] [Full Text] [Related] [New Search]