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  • Title: Differential effects of selective brain lesions on hypothalamic and pituitary ir-dynorphin.
    Author: Spampinato S, Candeletti S, Cavicchini E, Romualdi P, Speroni E, Ferri S.
    Journal: NIDA Res Monogr; 1986; 75():410-3. PubMed ID: 2893275.
    Abstract:
    Selective radiofrequency and neurotoxic lesions of the serotonergic pathways caused in the rat a significant reduction of ir-dynorphin A and B in the hypothalamus but not at pituitary level. These data confirm that dynorphin-related peptides are regulated independently in these areas.
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