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  • Title: A zebrafish homologue of the murine Hox-2.1 gene.
    Author: Njølstad PR, Molven A, Fjose A.
    Journal: FEBS Lett; 1988 Mar 28; 230(1-2):25-30. PubMed ID: 2895022.
    Abstract:
    Homeobox-containing sequences were isolated from a genomic library of zebrafish (Brachydanio rerio). A lambda clone containing two homeobox cross-hybridizing regions was characterized. DNA sequencing of one of these regions (ZF-21) revealed that it contains a homeobox closely related to the Antennapedia class of Drosophila homeobox sequences. Moreover, the deduced amino acid sequence of the C-terminal end (81 residues including the homeobox) is identical to the corresponding part of the murine Hox-2.1 protein. Similar to Hox-2.1, a ZF-21 derived transcript of 2.3 kb is present in embryos at the somite forming stages.
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