These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Interaction of acetyl-CoA carboxylase from the rat liver with analogs of activated carbon dioxide and ATP].
    Author: Amontov SV, Rabinkov AG, Tyrtysh TV, Tarusova NB, Goriachenkova EV.
    Journal: Mol Biol (Mosk); 1988; 22(1):195-200. PubMed ID: 2897623.
    Abstract:
    The interaction of rat liver Ac-CoA-carboxylase with reactive and stable analogs of carbon dioxide and phosphoric acid mixed anhydrides--hypothetic intermediate of the enzyme reaction--has been studied. Carbamoylphosphate showed substrate properties, whereas phosphonacetic acid and beta-oxopropyl-alpha, alpha-diphosphonate inhibited this enzyme (Ki 3.0 and 3.5 mM correspondingly). The analog of another possible intermediate in the reaction of ATP and carbon dioxide, Appp (CH2COOH) also inhibited Ac-CoA-carboxylase (Ki = 0.7 mM).
    [Abstract] [Full Text] [Related] [New Search]