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  • Title: Cytogenetic and clinical findings in mares with gonadal dysgenesis.
    Author: Trommershausen-Smith A, Hughes JP, Neely DP.
    Journal: J Reprod Fertil Suppl; 1979; (27):271-6. PubMed ID: 289800.
    Abstract:
    Gonadal dysgenesis in the mare is associated with several different karyotypes, including sex chromosome aneuploidy (63,X; 63,X/64,XX; 63,X/64,XY or 65,XXX), the normal male complement (64,XY) and autosomal deletion (64,XX?del2q-). The 63,X is the most common karyotype found in gonadal dysgenesis. Aneuploid cases probably represent spontaneous chromosome non-disjunction during oogenesis, spermatogenesis or early embryonic development. Cases with XY or autosomal deletion may be inherited defects or of spontaneous origin.
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