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  • Title: [Perazine-induced agranulocytosis--case report].
    Author: Möllering M.
    Journal: Z Kinder Jugendpsychiatr; 1988 Mar; 16(1):27-30. PubMed ID: 2898846.
    Abstract:
    This complication normally arises between the 5th and 10th weeks of treatment and is most commonly seen in middle-aged and elderly women. The risk is estimated to be between 0.04% and 2%, depending on the type of medication and the method of assessment. The present report describes a 16-year-old boy who developed agranulocytosis after 4 weeks of treatment with perazine. The problem was complicated by acute toxoplasmosis. After perazine was discontinued the neutrophils recovered within 5 days; the boy did develop fever, but the infectious disease had a mild course. This case report once again confirms the importance of regular blood control during the early phases of treatment with psychopharmacological agents.
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