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  • Title: Recognition of giant cell arteritis in patients with polymyalgia rheumatica who have a stroke: a cautionary tale.
    Author: Gutteridge DH, Mastaglia FL.
    Journal: Intern Med J; 2017 Oct; 47(10):1199-1201. PubMed ID: 28994265.
    Abstract:
    An 82-year-old woman with polymyalgia rheumatica (PMR) on prednisone 7 mg daily was admitted to an acute stroke unit with a right homonymous hemianopia, a left posterior cerebral artery occlusion and occipital lobe infarct. She had raised inflammatory markers, did not have a temporal artery biopsy, and was discharged on the same dose of prednisone. After 21 months, off prednisone, her ophthalmologist, concerned about giant cell arteritis (GCA), restarted prednisone 40 mg daily, with rapid, profound visual improvement. After 3 days her general practitioner, noting normal baseline inflammatory markers, stopped treatment-with rapid visual reversion. It is critical to recognise GCA in patients with PMR admitted to a stroke unit and not to withdraw prematurely corticosteroids once commenced.
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