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  • Title: [The effect of early visual deprivation on the synthesis of glutamic and aspartic acids in mitochondria of central structures of the visual analyzer in the dog].
    Author: Agaev TM, Kurbanova GA.
    Journal: Vopr Med Khim; 1988; 34(3):59-61. PubMed ID: 2901799.
    Abstract:
    After 45 days visual deprivation synthesis via direct reductive amination and transamination of glutamic and aspartic acids was inhibited in mitochondria of dog visual cortex, colliculi anterioris and corpus geniculatum externus. Under conditions of long-term (90 days) visual deprivation synthesis of glutamic and aspartic acids was less effectively inhibited in mitochondria of the brain areas studied via the reductive amination and transamination, except of the aspartic acid synthesis by means of transamination, the rate of which was maintained at the level similar to the values observed after 45 days of visual deprivation.
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