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  • Title: Chromosome mapping with DNA markers.
    Author: White R, Lalouel JM.
    Journal: Sci Am; 1988 Feb; 258(2):40-8. PubMed ID: 2903549.
    Abstract:
    New markers called RFLP's (for restriction-fragment length polymorphisms) can indicate the location on a chromosome of a disease-causing gene and serve to identify carriers. With enough markers one can map the human chromosomes--the first step toward an ambitious goal of molecular biology: sequencing the entire human genome.
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