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  • Title: Interventions and Outcomes in Patients with Infectious Pseudomonas scleritis: A 10-Year Perspective.
    Author: Ahmad S, Lopez M, Attala M, Galor A, Stanciu NA, Miller D, Suh L, Albini T, Perez VL, Karp CL, Davis JL, Alfonso E, Forster RK, Amescua G.
    Journal: Ocul Immunol Inflamm; 2019; 27(3):499-506. PubMed ID: 29040032.
    Abstract:
    Purpose: To identify interventional factors associated with improved visual results and faster time to resolution for patients with Pseudomonas scleritis. Methods: Retrospective study analyzing inciting factors, therapeutic modalities, and outcomes of patients with Pseudomonas scleritis. Results: A total of 24 patients were analyzed; 22 were treated as outpatients. All had resolution of infection and 58% (n = 14) maintained ≥20/200 vision. Medical therapy included topical and oral antibiotics; seven received additional subconjunctival injections; two were admitted for IV antibiotics. Patients presenting with ≥20/200 vision were more likely to maintain this level of vision (n = 8, 80%) compared to those presenting with severe vision loss (n = 5, 36%) (p = 0.04). A similar proportion of patients who received (n = 8, 61%) and did not receive (n = 5, 39%) oral steroids achieved 20/200 vision or better once infection resolved, p = 1.0. Conclusions: Pseudomonas scleritis can be successfully managed in the outpatient setting. Oral steroids do not appear harmful in the treatment of this disease.
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