These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Draft genome sequences of three multidrug-resistant Cutibacterium (formerly Propionibacterium) acnes strains isolated from acne patients, China.
    Author: Zhang N, Lu Z, Ma Y.
    Journal: J Glob Antimicrob Resist; 2017 Dec; 11():114-115. PubMed ID: 29051020.
    Abstract:
    OBJECTIVES: Cutibacterium acnes (formerly Propionibacterium acnes), an anaerobic Gram-positive bacterium, is a skin commensal and is considered to be associated with acne. Here we report the draft genome sequences of three multidrug-resistant (MDR) C. acnes strains (CA17, CA39 and CA51) isolated from skin lesions of acne patients in China. METHODS: The whole genomes of the three MDR C. acnes strains were sequenced using an Illumina HiSeq 2500 platform. De novo assembly and annotation were performed with SPAdes 3.5.0 and NCBI Prokaryotic Genome Annotation Pipeline (PGAP), respectively. RESULTS: The genomes of the three strains are as follows: 2 488 255bp containing 2494 genes and 2266 coding sequences (CDSs) for CA17; 2 484 088bp containing 2515 genes and 2376 CDSs for CA39; and 2 483 437bp containing 2515 genes and 2372 CDSs for CA51. Each strain has 45 tRNAs and 3 rRNAs. CONCLUSIONS: The genome sequences of the three MDR C. acnes strains may provide foundations for further research into the resistance mechanisms of antibiotic-resistant C. acnes strains and their role in disease pathogenesis.
    [Abstract] [Full Text] [Related] [New Search]