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  • Title: Prenatal diagnosis of thalassemia: experiences at the Shanghai Children's Hospital.
    Author: Zeng YT, Huang SZ, Zhang ML.
    Journal: Hemoglobin; 1988; 12(5-6):795-800. PubMed ID: 2905348.
    Abstract:
    Using DNA dot-blot hybridization, restriction endonuclease gene mapping with oligonucleotide probes, restriction fragment length polymorphism linkage analysis, and hybridization, prenatal diagnosis was performed for 32 pregnancies at risk for alpha-thalassemia and for 10 pregnancies at risk for beta-thalassemia. The DNA samples were prepared from chorion villi or amniotic fluid cells.
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