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  • Title: [Animal models of tardive dyskinesia].
    Author: Bédard PJ, Boucher R, DiPaolo T.
    Journal: Encephale; 1988 Sep; 14 Spec No():163-6. PubMed ID: 2905644.
    Abstract:
    It is possible to induce in monkeys abnormal movements of the mouth and tongue resembling strikingly tardive dyskinesia. Such movements can be induced by chronic treatment with neuroleptics or by lesions placed in the habenular interpeduncular tract or nucleus parafascicularis thalami. Dopaminergic D1 and D2 receptors are involved in the modulation of such movements.
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