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  • Title: Adverse effects with oral 5-aminosalicyclic acid.
    Author: Fardy JM, Lloyd DA, Reynolds RP.
    Journal: J Clin Gastroenterol; 1988 Dec; 10(6):635-7. PubMed ID: 2906645.
    Abstract:
    Two patients with ulcerative colitis and a past history of allergic reactions to sulfasalazine had similar reactions when treated with 5-aminosalicylic acid. This suggests that, at least in some patients, the adverse effects of sulfasalazine are due to 5-aminosalicylic acid rather than sulfapyridine. Desensitization to sulfasalazine was successfully carried out in one patient but was not attempted in a second.
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