These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Absence of a close linkage between Alzheimer's disease susceptibility gene and a polymorphic DNA probe coding for beta-amyloid.
    Author: David F, Lucotte G.
    Journal: Biomed Pharmacother; 1988; 42(9):575-7. PubMed ID: 2907297.
    Abstract:
    The hypothesis of a connection between Alzheimer's disease (AD) gene and the probe coding for beta-amyloid (beta-A), located on chromosome 21, was investigated in a large study group from Calabria, in which AD was transmitted as an autosomal dominant Mendelian trait. Segregation analysis of one EcoRI restriction polymorphism of beta-A, after molecular hybridization with a long cDNA probe of DNAs from key-individuals in the study group, determined that there was not a close connection between AD and beta-A.
    [Abstract] [Full Text] [Related] [New Search]