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  • Title: A Case of Congenital Infantile Fibrosarcoma of the Bowel Presenting as a Neonatal Intussusception.
    Author: Obayashi J, Koizumi H, Hoshikawa M, Wakisaka M, Fujikawa A, Kitagawa H, Takagi M.
    Journal: Pathol Int; 2017 Dec; 67(12):644-648. PubMed ID: 29090505.
    Abstract:
    Neonatal intussusception of the intestinal tract is rare. However, most neonatal intussusceptions have an organic lead point. For the lead point to be a neoplasm is extremely rare. We report a case that presented with neonatal intussusception with a congenital infantile fibrosarcoma as the lead point. The detection of ETV6-NTRK3 gene fusion was useful, although the definitive diagnosis was achieved by a comprehensive evaluation including this gene analysis, standard histology and immunohistochemistry. Neonatal intussusception should be suspected to be caused by a neoplasm. If pathological diagnosis is difficult, molecular analysis should be utilized to diagnose congenital infantile fibrosarcoma.
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