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  • Title: Adenocarcinoma of the endometrium and endometrioid carcinoma of the ovary associated with pregnancy.
    Author: Hoffman MS, Cavanagh D, Walter TS, Ionata F, Ruffolo EH.
    Journal: Gynecol Oncol; 1989 Jan; 32(1):82-5. PubMed ID: 2909453.
    Abstract:
    Nine well-accepted cases of endometrial carcinoma associated with pregnancy have been reported. A 10th patient is added and the cases are briefly summarized. At the time of her definitive surgery 6 weeks postpartum, our patient was also found to have a Stage I endometrioid ovarian carcinoma. Nine of the 10 cases have been well-differentiated adenocarcinoma or adenoacanthoma and the lesions have tended to be focal with minimal or no invasion. Given the small number of patients, conclusions regarding prognosis and treatment are difficult to make. However, in younger patients with noninvasive adenocarcinoma of the endometrium, the adnexa may be spared. Endometrioid adenocarcinoma of the ovary, discovered incidentally in our patient, is associated with a concomitant adenocarcinoma of the endometrium in 5-29% of cases, but the present case in which the lesions coexisted with pregnancy appears to be the first such report in the literature.
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