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  • Title: Three new cytotoxic oleanane triterpenoid saponins from Cylindrokelupha dalatensis.
    Author: Yan MY, Liu J, Xing S, Xiong GL, Pei LP, Ma BP, Liu P, Zhou WB.
    Journal: J Asian Nat Prod Res; 2018 Aug; 20(8):770-780. PubMed ID: 29110541.
    Abstract:
    Three new minor oleanane triterpenoid saponins, cylindrosides B (1), C (2), and D (3), were isolated from the seed of Cylindrokelupha dalatensis using chromatographic method. Their structures were established on the basis of the chemical and spectroscopic evidences. They displayed significant antitumor activity in vitro against HL60 cancer cell lines and IC50 values were 7.15 ± 0.63, 10.07 ± 0.97, and 4.74 ± 0.57 μM, respectively, by MTT method.
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