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  • Title: The panorama of cerebral palsy in Sweden part XII shows that patterns changed in the birth years 2007-2010.
    Author: Himmelmann K, Uvebrant P.
    Journal: Acta Paediatr; 2018 Mar; 107(3):462-468. PubMed ID: 29121418.
    Abstract:
    AIM: This was the 12th population-based study to explore the epidemiology of cerebral palsy (CP) in western Sweden. METHODS: From 2007 to 2010, there were 104 713 live births in the area. We analysed the birth characteristics, aetiology and neuroimaging findings, calculated the prevalence and compared the results with previous study cohorts. RESULTS: Cerebral palsy was found in 205 children, corresponding to a crude prevalence of 1.96 per 1000 live births. The gestational age-specific prevalence for <28 gestational weeks was 59.0 per 1000 live births, 45.7 for 28-31 weeks, 6.0 for 32-36 weeks and 1.2 for >36 weeks. Hemiplegia accounted for 44%, diplegia for 34%, tetraplegia for 5%, dyskinetic CP for 12% and ataxia for 3%. Neuroimaging showed maldevelopment in 12%, white matter lesions in 49%, cortical/subcortical lesions in 15% and basal ganglia lesions in 11%. The aetiology was considered prenatal in 38%, peri/neonatal in 38% and remained unclassified in 24%. CP due to term or near-term asphyxia had decreased. CONCLUSION: A nonsignificant decrease in CP prevalence was seen in term-born children. Hemiplegia was still the most prevalent CP type, while the prevalence of dyskinetic CP had decreased. One in two children had white matter lesions, indicating late second- or early third-trimester timing.
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