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  • Title: Efficacy of direct hemoperfusion with a polymyxin B-immobilized fiber column in miliary tuberculosis.
    Author: Kawano Y, Nagashima R, Morimoto S, Izutani Y, Yamasaki R, Nishida T, Iwaasa M, Ishikura H.
    Journal: Acute Med Surg; 2017 Jul; 4(3):311-315. PubMed ID: 29123880.
    Abstract:
    CASE: A 75-year-old woman presented with a 10-day history of intermittent fever, general fatigue, and progressive dyspnea. Although she had a low PaO2/FIO2 ratio, the cause of acute respiratory distress syndrome was not clear until day 9 in hospital. OUTCOME: We treated the patient with direct hemoperfusion with a polymyxin B-immobilized fiber column incidentally; the PaO2/FIO2 ratio improved following this therapy. Acid-fast bacilli, which were not seen in the sputum on admission, were detected in cultures from sputum, urine, bone marrow, liver biopsy, and blood samples, with a real-time polymerase chain reaction assay confirming tuberculosis. She was immediately transferred to a specialized tuberculosis hospital, and after a 3-month treatment, was discharged. CONCLUSION: Treatment with polymyxin B-immobilized fiber column may provide good results for pulmonary oxygenation in acute respiratory distress syndrome caused by tuberculosis.
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