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  • Title: Activation of the kallikrein-kinin system in bullet wounding.
    Author: Lewis DH, Bengtsson MB, Larsson J, Liljedahl SO.
    Journal: Acta Chir Scand Suppl; 1979; 489():225-30. PubMed ID: 291259.
    Abstract:
    Anesthetized pigs were wounded in the thigh with a spherical missile at an impact velocity of 1500 m/sec. Arterial blood samples were taken before injury and at frequent intervals up to 12 hours after injury. Unbound (free) and total kallikrein (kallikrein + prekallikrein) were analyzed with a chromogenic substrate (S-2302, Kabi, Sweden) in which enzyme activity is determined spectrophotometrically by the development of a yellow colour. The results indicate an activation of the kallikrein-kinin system in bullet wounding, the significance of which remains to be determined.
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