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  • Title: Purpura fulminans. A case for heparin therapy.
    Author: Chenaille PJ, Horowitz ME.
    Journal: Clin Pediatr (Phila); 1989 Feb; 28(2):95-8. PubMed ID: 2914417.
    Abstract:
    A 6.5-year-old boy developed purpura fulminans. He had no evidence of congenital protein C deficiency. He responded readily to heparin therapy with resolution of his coagulopathy. The coagulopathy resumed rapidly after heparin therapy was interrupted to allow for surgical procedures. Despite correction of his coagulopathy with heparin, surgical amputation of his leg was necessary because of inadequate perfusion.
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