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  • Title: [Pseudomyogenic hemangioendothelioma in the upper limb: A case report and literature review].
    Author: Mayoral-Guisado C, Toro-Zambrano W, López-Macías M, Ruíz-Guerrero A, Rubio-Fernández A, Díaz-Delgado M.
    Journal: Rev Esp Patol; 2017; 50(1):49-53. PubMed ID: 29179965.
    Abstract:
    Pseudomyogenic hemangioendothelioma, also called epithelioid sarcoma-like hemangioendothelioma, is a rare, vascular neoplasm usually with indolent behaviour. It was introduced in the latest World Health Organization (WHO) Classification of Tumours of Soft Tissue. We report a case of a 45 year-old patient presenting with a localized, palpable and slightly painful lesion in the left arm. Histologically it consisted of fascicles of spindle and epithelioid cells with ample eosinophilic cytoplasm, without nuclear pleomorphism or significant mitotic activity. Tumour cells showed diffuse expression for cytokeratin AE1/AE3, CD31 and FLI1, intact expression for INI1 and negativity for CD34. We describe the clinical, histological, molecular and immunohistochemical features of pseudomyogenic hemangioendothelioma and review the pertinent literature.
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