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Title: Doppler echocardiographic evaluation of right and left ventricular diastolic function in normal neonates.
Author: Riggs TW, Rodriguez R, Snider AR, Batton D.
Journal: J Am Coll Cardiol; 1989 Mar 01; 13(3):700-5. PubMed ID: 2918176.
Abstract:
Doppler echocardiograms of the tricuspid and mitral valves were recorded along with the electrocardiogram and respiration in 22 normal full-term neonates. A computer-interfaced digitizer pad was utilized to measure the following: peak E and A velocities (cm/s); E and A areas (the components of the total velocity-time integral in the early passive period of ventricular filling [E] and the late active period of atrial emptying [A], respectively) and the 1/3 area fraction (or the proportion of filling in the first 1/3 of diastole). All of the variables of right (tricuspid) versus left (mitral) ventricular filling were significantly different on the 1st day of life. Respective values were peak E velocity (cm/s) 44.6 +/- 10.0 (tricuspid) versus 53.2 +/- 9.3 (mitral), p less than 0.01; peak E/A ratio 0.84 +/- 0.14 versus 1.15 +/- 0.17, p less than 0.0001; E/total area 0.58 +/- 0.07 versus 0.63 +/- 0.05, p less than 0.005; E/A area ratio 1.05 +/- 0.23 versus 1.63 +/- 0.40, p less than 0.0001; 1/3 area fraction 0.31 +/- 0.04 versus 0.41 +/- 0.04, p less than 0.0001; peak A velocity (cm/s) 53.0 +/- 8.4 versus 47.6 +/- 5.8, p less than 0.05 and A/total area 0.57 +/- 0.09 versus 0.41 +/- 0.09, p less than 0.001; the mean heart rate (beats/min) was not significantly different: 121 +/- 8 versus 120 +/- 7. Most of the variables remained significantly different on the 2nd day of life, but the level of significance was the same or less for all measurements.(ABSTRACT TRUNCATED AT 250 WORDS)

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