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  • Title: [Hemostasis in cancer patients during radiation therapy using metronidazole].
    Author: Chekalina SI, Berdov BA, Pavlov VV, Andreev VG.
    Journal: Med Radiol (Mosk); 1989 Feb; 34(2):52-6. PubMed ID: 2918830.
    Abstract:
    Indices of platelet function, plasmic coagulation and fibrinolysis were studied during gamma-beam therapy in patients with laryngeal, gastric and cervical tumors (potentially at risk for thrombosis) against a background of metronidazole administration. During the above therapy the thrombophilic status of gastric cancer patients was preserved. These patients were considered at risk for thrombosis. In patients with laryngeal and cervical cancer platelet capacity to adhesion was considerably reduced during radiotherapy with the use of metronidazole. As a result of it the thrombogenic blood potential and danger of intravascular thrombogenesis were decreased.
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