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  • Title: Giardia duodenalis mouse model for the development of novel antigiardial agents.
    Author: Abraham RJ, O'Dea M, Rusdi B, Page SW, O'Handley R, Abraham S.
    Journal: J Microbiol Methods; 2018 Feb; 145():7-9. PubMed ID: 29198594.
    Abstract:
    This study describes a neonatal mouse model of Giardia infection for development of novel antigiardials. Mice were infected with the axenically cultured Assemblage A BAH2c2 strain, with 105 trophozoites per animal recovered. This model proved to be robust and consistent for use in preliminary drug efficacy trials and drug development.
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