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  • Title: [HLA-A, B, C phenotype frequencies in progressive systemic scleroderma].
    Author: Baldauf C, Schaller J, Herrmann K, Haustein UF.
    Journal: Dermatol Monatsschr; 1989; 175(1):16-9. PubMed ID: 2920860.
    Abstract:
    In 41 patients suffering from progressive systemic sclerosis (PSS) the phenotype frequencies of 28 HLA-A, B, C antigens were determined. Compared to 2947 blood donors the PSS patients exhibited an increase in the HLA-B8 frequency (37% versus 19%). This difference revealed to be not significant after the correction according to the number of antigens tested. The same was with the increase in the frequency of HLA-B5, B13, B27, Cw2 and the decrease in the frequency of HLA-A2, B12, B14, B15, B4 and Cw3. The results were compared with the data reported in the literature. Additionally, there were no differences when compared the diffuse PSS with the acral form and CREST, respectively.
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