These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: A laminin-like adhesive protein concentrated in the synaptic cleft of the neuromuscular junction.
    Author: Hunter DD, Shah V, Merlie JP, Sanes JR.
    Journal: Nature; 1989 Mar 16; 338(6212):229-34. PubMed ID: 2922051.
    Abstract:
    A striking example of topographic specificity in synapse formation is the preferential reinnervation of original synaptic sites on denervated muscle fibres by regenerating motor axons. This specificity is mediated by the basal lamina of the synaptic cleft. A glycoprotein, s-laminin, has now been identified that is selectively associated with synaptic basal lamina and is recognized by motoneurons. Molecular cloning reveals that s-laminin is a novel homologue of laminin, a potent promoter of neurite outgrowth.
    [Abstract] [Full Text] [Related] [New Search]