These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Dominantly inherited childhood gigantism resembling Sotos' syndrome.
    Author: Blackett PR, Coffman MA, Schaefer GB, Rennert OM.
    Journal: Am J Med Sci; 1989 Mar; 297(3):181-5. PubMed ID: 2923142.
    Abstract:
    Excessive growth in infancy and onset of puberty at age four was observed in a boy with features resembling Sotos syndrome. Early development of secondary sexual characteristics and advanced osseous maturation were observed. The family history was significant; excessive weight gain tended to occur in female family members in association with rapid growth in infancy and childhood. A delayed insulin response to glucose was observed in both mother and sister, and diabetes developed during his mother's gestation. These observations suggest that undetermined factors associated with excessive growth may be inherited as a dominant trait with variable expression.
    [Abstract] [Full Text] [Related] [New Search]