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  • Title: A self-assessed photosensitizer: inducing and dual-modal phosphorescence imaging of mitochondria oxidative stress.
    Author: Yang J, Cao Q, Hao L, Yang GG, Hu WL, Ji LN, Mao ZW.
    Journal: Chem Commun (Camb); 2018 Jan 02; 54(3):271-274. PubMed ID: 29231930.
    Abstract:
    Two novel Ir(iii)-nitroxide conjugates have been synthesized as mitochondria-targeted multi-functional theranostic photosensitizers, capable of simultaneously inducing and dual-modal phosphorescence imaging of mitochondrial oxidative stress under two-photon excitation, thus realizing the photodynamic therapy of cancer and self-assessment of their PDT efficacies.
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