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  • Title: 2-Deoxy-D-glucose accumulation in adipocytes: apparent transport discrimination between 2-deoxy-D-glucose and 3-O-methyl-D-glucose.
    Author: Thompson KA, Kleinzeller A.
    Journal: Biochim Biophys Acta; 1989 Mar 28; 1011(1):58-60. PubMed ID: 2923870.
    Abstract:
    The uphill accumulation of free 2-deoxy-D-glucose and 2-deoxy-D-glucose 6-phosphate in rat adipocytes was found not to affect the steady-state distribution of 3-O-methyl-D-glucose although both hexoses share a common transport pathway. This observation argues against a possible effect of 2-deoxy-D-glucose phosphate on the equilibrating nature of the carrier. The results are discussed in light of hypotheses advanced to explain free 2-deoxy-D-glucose accumulation in a variety of cells.
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