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  • Title: Administration of L-2-oxothiazolidine-4-carboxylate increases glutathione levels in rat brain.
    Author: Mesina JE, Page RH, Hetzel FW, Chopp M.
    Journal: Brain Res; 1989 Jan 23; 478(1):181-3. PubMed ID: 2924114.
    Abstract:
    Sterile L-2-oxothiazolidine-4-carboxylate, given as a neutral 100 mmol solution at a dose of 8 mmol/kg subcutaneously, caused an increase in total glutathione concentration in the brain of treated rats. This finding could be important in understanding the role of glutathione in the central nervous system.
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