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  • Title: Acute myocardial infarction due to coronary spasm associated with L-thyroxine therapy.
    Author: Hiasa Y, Ishida T, Aihara T, Bando M, Nakai Y, Kataoka Y, Mori H.
    Journal: Clin Cardiol; 1989 Mar; 12(3):161-3. PubMed ID: 2924444.
    Abstract:
    A 63-year-old man with hypothyroidism is described. He had been receiving L-thyroxine therapy following mitral valve surgery. About three weeks into the therapy regimen, he complained of severe retrosternal chest oppression. Electrocardiographic findings and laboratory data indicated a diagnosis of acute myocardial infarction due to the L-thyroxine therapy. Emergency selective coronary angiography was performed. Comparing his coronary angiograms with those obtained before surgery indicated a severely spastic left coronary artery. We believe this is the first report of myocardial infarction due to coronary spasm, demonstrated by angiography associated with L-thyroxine therapy.
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