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  • Title: Characteristics of the Choriocapillaris Layer in Optical Coherence Tomography Angiography of Acute Central Serous Chorioretinopathy.
    Author: Qu Y, Gong D, Yu W, Dong F.
    Journal: Ophthalmic Surg Lasers Imaging Retina; 2017 Dec 01; 48(12):1000-1005. PubMed ID: 29253303.
    Abstract:
    BACKGROUND AND OBJECTIVE: To describe the vascular characteristics of the choriocapillaris layer in acute central serous chorioretinopathy (CSC) imaged by optical coherence tomography angiography (OCTA), and to analyze the vascular density. PATIENTS AND METHODS: Retrospective, observational case series. In the study, 20 eyes of patients with acute CSC and 20 normal individuals were selected. All underwent OCTA, and 3 mm × 3 mm scanning mode was chosen for analyzing vascular density and morphological characteristics on the choriocapillaris layer. RESULTS: A dark region with some hyperreflective signal spots on the choriocapillaris layer was found in all affected eyes' OCTA images. The choroidal vascular density (CVD) in the affected eyes was significantly lower than in the normal eyes (P = .000 vs. P < .05). Additionally, the density of affected eyes was much smaller in comparison with the fellow eyes, which was statistically significant (P = .000 vs. P < .05). Fellow eyes' density was also lower than in normal eyes (P = .009 vs. P < .05). CONCLUSION: OCTA could offer a new approach to help understand the mechanisms of changes in the choriocapillary with imaging and provide quantitative analysis, as well. [Ophthalmic Surg Lasers Imaging Retina. 2017;48:1000-1005.].
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