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Title: Triterpenoid saponins from the pulp of Sapindus mukorossi and their antifungal activities. Author: Hu Q, Chen YY, Jiao QY, Khan A, Li F, Han DF, Cao GD, Lou HX. Journal: Phytochemistry; 2018 Mar; 147():1-8. PubMed ID: 29257999. Abstract: Under the guidance of anti-fungal bioassay, four previously undescribed oleanane-type and one lupane-type triterpenoid saponins, along with twelve known analogues, were isolated from the extract of Sapindus mukorossi pulps. Their structures were determined on the basis of spectroscopic analysis and chemical methods. In vitro biotests, oleanolic acid 3-O-β-D-xylopyranosyl-(1 → 3)-α-L-rhamnopyranosyl-(1 → 2)-α-L-arabinopyranoside showed inhibitory activity against Trichophyton rubrum with MIC80 value of 8 μg/mL, while oleanolic acid 3-O-α-L-arabinopyranosyl-(1 → 3)-α-L-rhamnopyranosyl-(1 → 2)-α-L-arabinopyranoside exhibited inhibitory activity against both Trichophyton rubrum and Candida albicans with MIC80 values of 8 μg/mL.[Abstract] [Full Text] [Related] [New Search]