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  • Title: Normal values for calprotectin in stool samples of infants from the population-based longitudinal born into life study.
    Author: Peura S, Fall T, Almqvist C, Andolf E, Hedman A, Pershagen G, Helmersson-Karlqvist J, Larsson A.
    Journal: Scand J Clin Lab Invest; 2018; 78(1-2):120-124. PubMed ID: 29283308.
    Abstract:
    Faecal calprotectin is a protein used as a diagnostic marker for inflammatory bowel diseases. We determined upper limits for normal calprotectin values for neonatal, 6, 12 and 24 months old children using a turbidimetric immunoassay in a cohort of Swedish children. The advantage of the method is that opposite to previously used enzyme-linked immunosorbent assay (ELISA) method, it enables measuring single samples, and thus, shortens the analysis time significantly. There were 72 samples (41.7% female) collected neonatally, 63 samples (34.9% female) at 6 months, 60 samples (40.0% female) at 12 months and 51 samples (43.1% female) at 24 months. The upper limits for normal values were 233, 615, 136 and 57 µg mg-1 for infants aged 0, 6, 12 and 24 months, respectively.
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