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  • Title: The role of three phase bone scintigraphy in arthroplasty of hip and knee joints of clean-up workers of Chornobyl accident.
    Author: Tkachenko MM, Korol PO.
    Journal: Probl Radiac Med Radiobiol; 2017 Dec; 22():476-483. PubMed ID: 29286528.
    Abstract:
    OBJECTIVE: The objective of the work to determine the diagnostic role of the three phase bone scintigraphy (3 F BS) in the early prediction of paraendoprosthetic complications of the hip and knee joints of the participants in clean up workers of Chornobyl accident. MATERIAL AND METHODS: The 3 F BS method were investigated the radionuclide kinetic parameters of the inclusion and distribution of radiopharmaceuticals (RF) in damaged joints in the 75 male clean up workers. RESULTS: It was established that calculating the quantitative indices of kinetics of the drug at various stages of the 3 F BS allowed to determine statistically significant differences in metabolic changes in focal lesions in articular structures. Thus, the differential diagnostic capabilities of the radionuclide method of examination of patients with arthroplasty of the hip and knee joints are elevated. CONCLUSIONS: The kinetics of osteotropic RF in the foci of fixing the damaged hip and knee joints in the infectious and inflammatory processes is characterized by the predominance of retention and specific accumulation of the drug in the early static phase and the delayed static phase of the 3 F BS compared with the centers of fixation of RF in deforming osteoarthroses, which correlates with the differences in destructive reparative processes in them. Meta: vyznachyty diagnostychnu rol' tryfazovoï osteostsyntygrafiï (3 f OSG) u rann'omu prognozuvanni paraen doproteznykh uskladnen' kul'shovykh i kolinnykh suglobiv uchasnykiv likvidatsiï naslidkiv avariï na ChAES. Material ta metody. U 75 patsiientiv cholovichoï stati, iaki braly uchast' u likvidatsiï naslidkiv avariï na ChAES z ura zhenniamy kul'shovykh i kolinnykh suglobiv riznogo genezu, metodom 3 f OSG doslidzheno radionuklidni kinetychni pa rametry vkliuchennia ta rozpodilu radiofarmpreparatu (RFP) v diliankakh ushkodzhenykh suglobiv.Rezul'taty. Vstanovleno, shcho obchyslennia kil'kisnykh pokaznykiv kinetyky indykatora na riznykh etapakh 3 f OSG dozvolylo vyznachyty statystychno dostovirni vidminnosti metabolichnykh zmin pry vognyshchevykh urazhenniakh v sug lobovykh strukturakh. Tym samym pidvyshcheno dyferentsiy̆no diagnostychni mozhlyvosti radionuklidnogo metodu obs tezhennia khvorykh pry endoprotezuvanni kul'shovykh i kolinnykh suglobiv.Vysnovky. Kinetyka osteotropnykh RFP v oseredkakh fiksatsiï urazhenykh kul'shovykh i kolinnykh suglobiv pry infektsiy̆no zapal'nykh protsesakh kharakteryzuiet'sia perevazhanniam retentsiï ta pytomogo nakopychennia preparatu v ranniy̆ statychniy̆ fazi i vidstrocheniy̆ statychniy̆ fazi 3 f OSG porivniano z vognyshchamy fiksatsiï RFP pry defor muiuchykh osteoartrozakh, shcho koreliuie z vidminnostiamy destruktyvno reparatyvnykh protsesiv u nykh.
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