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  • Title: Coordination-driven self-assembly of a Pt(iv) prodrug-conjugated supramolecular hexagon.
    Author: Yue Z, Wang H, Li Y, Qin Y, Xu L, Bowers DJ, Gangoda M, Li X, Yang HB, Zheng YR.
    Journal: Chem Commun (Camb); 2018 Jan 18; 54(7):731-734. PubMed ID: 29303526.
    Abstract:
    This article presents a new strategy to engage coordination-driven self-assembly for platinum drug delivery. The self-assembled supramolecular hexagon is conjugated with three equivalents of Pt(iv) prodrugs and displays a superior therapeutic index compared to cisplatin against a panel of human cancer cell lines.
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