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  • Title: Non-immediate heparin and heparinoid cutaneous allergic reactions: a role for fondaparinux.
    Author: Tan E, Thompson G, Ekstrom C, Lucas M.
    Journal: Intern Med J; 2018 Jan; 48(1):73-77. PubMed ID: 29314514.
    Abstract:
    Non-immediate allergic cutaneous reactions to heparins have been increasingly reported, typically manifesting as large, eczematous plaques at sites of subcutaneous injection. Patients may demonstrate cross-reactivity between unfractionated heparin, low molecular weight heparin and semi-synthetic heparinoids, making finding an alternative difficult. Fondaparinux has been identified as a useful alternative in such patients; here we present the first two documented cases in Australia and a literature review.
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