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  • Title: Immunoreactive SOD-1 in amniotic fluid, amniotic cells and fibroblasts from trisomy 21 fetus.
    Author: Baeteman MA, Mattei MG, Baret A, Gamerre M, Mattei JF.
    Journal: Acta Paediatr Scand; 1985 Sep; 74(5):697-700. PubMed ID: 2931942.
    Abstract:
    Copper superoxide dismutase (Cu-SOD or SOD-1) was measured by radioimmunoassay (RIA) in amniotic cells and fluid as well as in fetal trisomy 21 fibroblasts. The significant increase of the SOD-1 activity observed in amniotic cells and fetal trisomy 21 fibroblasts demonstrates the early physiopathogenic expression of the supernumerary chromosome 21 in affected patients.
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