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  • Title: Oleanane-type triterpenoid saponins from Lysimachia fortunei Maxim.
    Author: Zhang SL, Yang ZN, He C, Liao HB, Wang HS, Chen ZF, Liang D.
    Journal: Phytochemistry; 2018 Mar; 147():140-146. PubMed ID: 29324278.
    Abstract:
    Six previously undescribed oleanane-type triterpenoid saponins, fortunosides A-F, together with six known ones, were isolated from the aerial parts of Lysimachia fortunei Maxim. Their structures were established by spectroscopic data analyses (1D, 2D-NMR and HRESIMS) and chemical methods. All isolated triterpenoid saponins were evaluated for their cytotoxicity against four human liver cancer cell lines (SMMC-7721, Hep3B, HuH7, and SK-Hep-1). Three saponins with the aglycone protoprimulagenin A exhibited moderate cytotoxicity against all of the tested human cancer cell lines, with IC50 values ranging from 4.76 to 15.12 μM.
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