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  • Title: Leser-Trélat sign associated with Sézary syndrome.
    Author: Horiuchi Y, Katsuoka K, Tsukamoto K, Takezaki S.
    Journal: Cutis; 1985 Nov; 36(5):409-10. PubMed ID: 2933229.
    Abstract:
    The Leser-Trélat sign is a rare but well known cutaneous indicator of internal malignancy, most commonly adenocarcinoma of the stomach. There have been only a few cases associated with lymphoproliferative malignancies. Sézary syndrome is a chronic leukemia/lymphoma characterized by generalized erythroderma and circulating Sézary cells. We describe a rare case of the Leser-Trélat sign associated with the Sézary syndrome. The skin sign was alleviated through combination chemotherapy.
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