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  • Title: The effect of reduced activity on the enzymatic development of phasic and tonic muscles in the chicken.
    Author: Moore GE, Goldspink G.
    Journal: J Dev Physiol; 1985 Dec; 7(6):381-6. PubMed ID: 2934467.
    Abstract:
    The effects of reduced activity (immobilisation) on the development of the contractile enzyme, Mg2+-activated myofibrillar ATPase was studied in a tonic muscle, the anterior latissimus dorsi and in a phasic muscle, the posterior latissimus dorsi of the chicken. Mg2+-activated myofibrillar ATPase activity showed a decreased and delayed activity peak in both the immobilised muscles. Large differences between the two muscles were observed using this marker enzyme. These data indicate that the activity of Mg2+-activated myofibrillar ATPase and the associated differential gene expression involved in fibre type differentiation are influenced by the early activity pattern of the muscles.
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