These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Brainstem findings in Huntington's disease. Possible mechanisms for slow vertical saccades.
    Author: Leigh RJ, Parhad IM, Clark AW, Buettner-Ennever JA, Folstein SE.
    Journal: J Neurol Sci; 1985 Dec; 71(2-3):247-56. PubMed ID: 2935595.
    Abstract:
    Quantitative, morphometric studies of the rostral interstitial nucleus of the medial longitudinal fasciculus (riMLF) were performed on the brains of four patients with Huntington's disease (HD) who had shown slow vertical saccades, and on the brains of three control subjects. Only one HD brain showed a statistically significant decrease in the number of larger neurons in the riMLF though all four brains showed non-specific gliosis. Taken with results from physiological and other clinical studies, the present data suggest that slow vertical saccades in HD are due, at least in part, to disordered inputs to the riMLF.
    [Abstract] [Full Text] [Related] [New Search]