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  • Title: [Homozygotic C5 deficiency disclosed by purulent Neisseria meningitidis meningitis].
    Author: Cesbron JY, Maillet F, Valance J, Langlet N, Kazatchkine M.
    Journal: Presse Med; 1985 Dec 21; 14(45):2287-9. PubMed ID: 2935813.
    Abstract:
    The complement system functions to protect the individual against infectious agents. Deficiencies of the late-acting complement proteins C5-C8 are associated with an increased susceptibility to Neisseria infection. This paper describes a deficiency in C5 in a Caucasoid family from the north of France that was revealed by the occurrence of a N. meningitidis meningitis in the homozygous C5-deficient propositus.
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