MEDLINE/PubMed Journal Browser Search

Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

Title: [Analysis of pregnancy outcomes of polycystic ovary syndrome patients after frozen embryo transfer].
Author: Lyu XD, Qiao J.
Journal: Zhonghua Fu Chan Ke Za Zhi; 2018 Jan 25; 53(1):31-34. PubMed ID: 29374883.
Abstract:
Objective: To investigate pregnancy outcomes of the patients with polycystic ovary syndrome (PCOS) after frozen embryo transfer (FET) . Methods: Data of 2 367 PCOS patients received in vitro fertilization-embryo transfer [including fresh embryo transfer (fET) and FET] from January 2009 to December 2015 in Peking University Third Hospital were evaluated retrospectively. The basal characteristics, pregnancy complications and outcomes were analyzed, then identified the relative factors followed. Results: Totally 2 367 patients received in vitro fertilization-embryo transfer: 1 106 were treated with fET, and the rest 1 261 cases were treated with FET. The incidence of gestational diabetes mellitus (GDM) was lower in FET group [4.04%(51/1 261) versus 6.15%(68/1 106)], the difference was statistically significant (P<0.05). Singletons born after FET had higher birth weight than fET [(3 406±548) versus (3 360±533) g], the difference was statistically significant (P<0.05). There was no difference of other pregnancy complications between the two groups (all P>0.05). fET was an independent risk factor for GDM (adjusted OR=1.570, 95%CI: 1.075-2.294). Conclusion: Compared with fET, FET could decrease the risk of GDM and receive better neonatal outcomes in patients with PCOS. 目的： 探讨解冻周期胚胎移植对多囊卵巢综合征（PCOS）患者妊娠结局的影响。 方法： 对2009年1月至2015年12月在北京大学第三医院行体外受精-胚胎移植治疗后获得单胎妊娠、并于孕28周后分娩的PCOS患者共2 367例，胚胎移植分为新鲜周期移植（1 106例）和解冻周期移植（1 261例）。收集并分析患者的孕前、妊娠期及分娩期的相关临床资料。 结果： 解冻周期移植的PCOS患者妊娠期糖尿病（GDM）的发生率显著低于新鲜周期移植者，分别为4.04%（51/1 261）、6.15%（68/1 106），两者比较，差异有统计学意义（P<0.05）。解冻周期移植的PCOS患者分娩孕周及新生儿出生体质量均显著大于新鲜周期移植者，分别为（38.8±2.0）、（38.4±1.9）周及（3 406±548）、（3 360±533）g，分别比较，差异均有统计学意义（P均<0.05）。其他产科并发症比较，差异均无统计学意义（P均>0.05）。新鲜周期移植是GDM的高危因素（校正OR=1.570，95%CI为1.075~2.294）。 结论： 解冻周期胚胎移植可能减少PCOS患者发生GDM，改善新生儿结局。.

[Abstract] [Full Text] [Related] [New Search]