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  • Title: Generation of B suppressor cells by phytohaemagglutinin.
    Author: Farkas R, Manor Y, Klajman A.
    Journal: Immunology; 1986 Mar; 57(3):395-8. PubMed ID: 2937719.
    Abstract:
    Activation by phytohaemagglutinin-P (PHA-P) of B cells from peripheral blood of healthy subjects generated B suppressor cells which inhibited allogeneic mixed lymphocyte reactions (MLR) and PHA-induced DNA synthesis. Their action was direct, that is, not mediated through the induction of T suppressor cells. The finding that B cells can be induced by PHA to become highly effective suppressor cells may have important clinical and experimental implications.
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