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  • Title: Zeolitic imidazolate framework-based biosensor for detection of HIV-1 DNA.
    Author: Pan Y, Zhan S, Xia F.
    Journal: Anal Biochem; 2018 Apr 01; 546():5-9. PubMed ID: 29382468.
    Abstract:
    ZIF-8(zinc-methylimidazolate framework-8), one of the zeolitic imidazolate frameworks (ZIFs), as quenching platforms for detection of HIV-1 DNA, which was identified to be effective for highly sensitive detection of HIV-1 DNA. The enhanced fluorescence signal has a relationship with the ssDNA concentration, the detection limit is as low as 1.2 nmol L-1 with good selectivity. This study is an important step toward rational design of materials to achieve specific interactions between biomolecules and synthetic particle surfaces.
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