These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Comparative studies of fresh and postmortem isolated rat cortical synaptosomes: uptake and potassium-evoked release of gamma-aminobutyric acid.
    Author: Kálmán M, Armenian AA, Chiflikian MD, Csillag A.
    Journal: Acta Biol Hung; 1985; 36(1):87-91. PubMed ID: 2938380.
    Abstract:
    Synaptosomal fractions were isolated from rat cerebral cortex immediately after decapitation and after 2 h and 4 h postmortem storage at room temperature. Uptake and release of [3H]GABA was compared between fresh and postmortem synaptosomal fractions. The results suggest that after a 2 h postmortem storage these functions are still comparable to those observed in fresh preparations, while a 4 h period of storage decreases them by about 50%. The present data are consistent with our previous findings that the 2 h postmortem fractions are comparable to freshly isolated fractions with respect to coupled respiration, potassium accumulation and capability of specific configurational changes.
    [Abstract] [Full Text] [Related] [New Search]