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  • Title: [Macroscopic fluctuations of the kinetic activity of alcohol dehydrogenase].
    Author: Evdokimov EV.
    Journal: Biofizika; 1986; 31(2):200-3. PubMed ID: 2938637.
    Abstract:
    Macroscopic fluctuations of liver alcohol dehydrogenase enzymic activity in complex reaction consisting in ethanol oxidation and butyraldehyde reduction were studied. It was found that maximal fluctuation amplitude was observed when the rates of both reactions were equal. Such dependence indicates connection between macroscopic fluctuations in alcohol dehydrogenase reaction and oscillations of relative affinity of the enzyme to oxidized and reduced coenzyme forms.
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